Breakthrough In Prodrug Project

laboratory vial with cystinosis foundation uk logoA new research paper has been published as a result of the work undertaken at the University of Sunderland to develop a prodrug for the treatment of cystinosis. Cystinosis Foundation UK has been able to support the prodrug project thanks to generous donations and fundraising efforts by our supporters.

The paper explains that “successful uptake and release of cysteamine was observed in cultured kidney cells“, meaning the prodrugs “show potential as novel delivery vehicles of cysteamine to improve the treatment of the genetic disorder nephropathic cystinosis.“. To put this more simply, the results are very promising, this is a big step towards the ultimate aim, which would be for prodrugs to replace cysteamine as the main treatment for cystinosis.

The full research paper is available to view at this link: http://authors.elsevier.com/a/1SMlg_55HFO7Sj

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