Our thanks go to Roz Anderson and Lisa Frost at Sunderland University for allowing us to publish their research poster, which was recently presented at the International Cystinosis Conference in Lignano, near Venice, in Italy.
The team at Sunderland University are, with financial support from the Cystinosis Foundation UK, researching prodrugs that would avoid some of the negative side effects of the current Cysteamine based medicines, such as bad breath and nausea. In addition, prodrugs can be targeted to release at appropriate points in the body, resulting in a more efficient absorption of Cysteamine and reducing the frequency that medicines need to be taken (from the current "every six hours").
Their research has shown positive results for a range of compounds and the team now hope to focus their efforts on finding the most suitable of these compounds.
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